121 research outputs found

    Graphical image persistence and code generation for object oriented databases

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    Attached is the detailed description of the design and implementation of graphical image persistence and code generation for object oriented databases. Graphical image persistent is incorporated into a graphics editor called OODINI. OODINI creates and manipulates graphical schemas for object-oriented databases. This graphical image on secondary storage is then translated into an abstract, generic code for dual model databases. This abstract code, DAL can then be converted into different dual model database languages. We provide an example by generating code for the VODAK Data Modeling language. It is also possible to generate a different abstract language code, OODAL from a graphical schema. This language does not have any dual model database architectural dependencies

    N—H⋯N hydrogen bonding in 4,6-diphenyl-2-pyrimidinylamine isolated from the plant Justicia secunda (Acanthaceae)

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    The title compound, C₁₆H₁₃N₃, isolated from Justicia secunda (Acanthaceae), comprises two molecules (which differ slightly in conformation) in the asymmetric unit of space group P\overline 1. Intermolecular Namino-H...Npyrm interactions (Npyrm is a pyrimidine ring N atom) involve only one of the two donor amino H atoms and pyrimidine N atoms per molecule, forming dimeric units via R²₂(8) rings, with N...N distances of 3.058 (2) and 3.106 (3) Å, and N-H...N angles of 172.7 (18) and 175.8 (17)°. The dimers are linked by C-H...π(arene) contacts, with an H...centroid distance of 2.77 Å and a C-H...centroid angle of 141°

    Q-Pandora Unboxed: Characterizing Noise Resilience of Quantum Error Correction Codes

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    Quantum error correction codes (QECCs) are critical for realizing reliable quantum computing by protecting fragile quantum states against noise and errors. However, limited research has analyzed the noise resilience of QECCs to help select optimal codes. This paper conducts a comprehensive study analyzing two QECCs - rotated and unrotated surface codes - under different error types and noise models using simulations. Among them, rotated surface codes perform best with higher thresholds attributed to simplicity and lower qubit overhead. The noise threshold, or the point at which QECCs become ineffective, surpasses the error rate found in contemporary quantum processors. When confronting quantum hardware where a specific error or noise model is dominant, a discernible hierarchy emerges for surface code implementation in terms of resource demand. This ordering is consistently observed across unrotated, and rotated surface codes. Our noise model analysis ranks the code-capacity model as the most pessimistic and circuit-level model as the most realistic. The study maps error thresholds, revealing surface code's advantage over modern quantum processors. It also shows higher code distances and rounds consistently improve performance. However, excessive distances needlessly increase qubit overhead. By matching target logical error rates and feasible number of qubits to optimal surface code parameters, our study demonstrates the necessity of tailoring these codes to balance reliability and qubit resources. Conclusively, we underscore the significance of addressing the notable challenges associated with surface code overheads and qubit improvements.Comment: 15 pages; 9 figures; 3 table

    Biphasic Effect of Phyllanthus emblica L. Extract on NSAID-Induced Ulcer: An Antioxidative Trail Weaved with Immunomodulatory Effect

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    Amla (Phyllanthus emblica L.), apart from its food value, can be used as a gastroprotective agent in non steroidal anti-inflammatory drug (NSAID)-induced gastropathy. It has been suggested that the antioxidative property of amla is the key to its therapeutic effect. Hence, on the basis of in vitro antioxidative potential, the ethanolic extract of amla (eAE) was selected for in vivo study in NSAID-induced ulcer. Intriguingly, eAE showed biphasic activity in ulcerated mice, with healing effect observed at 60 mg/kg and an adverse effect at 120 mg/kg.The dose-dependent study revealed that switching from anti-oxidant to pro-oxidant shift and immunomodulatory property could be the major cause for its biphasic effect, as evident from the total antioxidant status, thiol concentration, lipid peroxidation, protein carbonyl content followed by mucin content, PGE2 synthesis and cytokine status. Further, Buthionine sulfoxamine (BSO) pretreatment established the potential impact of antioxidative property in the healing action of eAE. However, eAE efficiently reduced pro-inflammatory cytokine (TNF-α and IL-1β) levels and appreciably upregulate anti-inflammatory cytokine (IL-10) concentration. In conclusion, gastric ulcer healing induced by eAE was driven in a dose-specific manner through the harmonization of the antioxidative property and modulation of anti-inflammatory cytokine level

    Marketing of Tourism Destination in the Context of Tiger Safari

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    Tiger tourism plays a significant role in the overall scenario of Indian tourism. The forest destination managers face a major challenge in satisfying their visitors since tigers are elusive by nature and most of the time tourists return dissatisfied without sighting a tiger after a forest safari. This paper is the first scientific study of its kind based on empirical data in the context of tiger tourism and proposed a model to identify the optimum path in the forest with a higher probability of tiger sighting

    Changing profile of GAD and IA-2 antibody positivity in Indian children with recently diagnosed type 1 diabetes mellitus

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    Introduction. Published literature on type 1 diabetes (T1DM) patients from India suggests that a substantial number of them are negative to GAD 65 and IA-2 an­tibodies. Antibody positivity rates have been linked to dietary and socio-economic factors and more recently, to changes in the enterobiome. Our anecdotal evidence indicated that antibody positivity rates among newly diagnosed T1DM children were rising. In this presen­tation we have formally collated our data on these antibodies, a first, we believe, in the Indian pediatric population. Material and methods. T1DM was diagnosed by stand­ard clinical criteria advocated by American Diabetes Association including in all patients, the presence of diabetic ketoacidosis (DKA). We used plasma blood glucose rather than A1C to diagnose the acute onset of type 1 diabetes in individuals with symptoms of hy­perglycemia. All patients with this diagnosis had GAD (glutamic acid decarboxylase) and IA-2 (insulinoma antigen 2) antibodies measured as a routine procedure from 2007. Data on patients between the ages of 1 and 16 years as on 31st August 2016 were collected for this study. The antibodies were measured by standard RIA kits from the same manufacturer and performed in the endocrinology laboratory of one of the institutions. Results. We included 694 T1DM cases from 2007 till 2016, out of which 296 were antibody positive. A total of 172 were GAD antibody positive, 62 were IA-2 anti­body positive and 90 exhibited dual antibody positivity (GAD positive + IA-2 positive). The chi-square test for trend analysis showed a significant rising trend for IA-2 antibody alone positive (p < 0.001, chi-square for trend = 17.437, df = 1) and either antibody positive percentages (p < 0.001, chi-square for trend = 22.71, df = 1), but not in the GAD antibody positivity (p = 0.059, chi-square for trend = 3.567, df = 1) and in dual antibody positive percentages (p = 0.486, chi-square for trend = 0.485, df = 1) over a period of 9 years i.e. from 2007 to 2016. Conclusion. Antibody positivity rates in recently di­agnosed T1DM children have changed fairly rapidly over the last nine years. This surge in autoimmunity may also be a significant contributing factor towards the recent increased incidence of T1DM in India

    Enhancement of post harvest fruit quality and leaf curl disease tolerance in tomato through hybrid breeding

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    Development of hybrids tolerant to leaf curl virus disease along with good post harvest/processing traits is the major thrust areas in tomato breeding now-a-days. A study was undertaken following 7 × 7 half diallel mating design utilizing four exotic and three indigenous lines to identify potential donors and crosses, to study the extent of heterobeltiosis and dominance behaviour, and to assess the genetic control of post harvest quality traits along with disease tolerance in tomato. Breeding strategies to improve characters governed by different types of gene action are discussed. Two parental lines, CLN 2777F and CLN 2777E could be utilized further in tomato breeding programme as they were identified as the most promising general combiners for fruit yield, processing quality and ToLCV tolerance. The maximum extent of heterobeltiosis (104.17%) was found in pericarp thickness followed by fruit yield plant-1 (63.57 %) and PDI of ToLCV disease (-60.00 %). The hybrids also exhibited various degrees of dominance effects. The study could also able to identify a promising cross ‘CLN 2777E × CLN 2777F’ which could be recommended for commercial exploitation after critical study in leaf curl disease prone areas of the tropics and sub-tropics
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